Hi! Wonders seem to happen once in a while. Finally I got graph-tool running on my Lion machine. Here are my steps which lead to a running graph-tool: 1. deinstall Macports python 2.7 such that it is never in the way (reinstall whatever you need in macports with python with the python26 branch) 2. install boost 1.47.0 into $HOME/.local; linked against python 2.7 from apple 3. install numpy/scipy from the SuperPack, see scipy.org 4. install cgal 3.9 with gmp and other dependencies coming from macports; install dir is $HOME/.local 5. grab graph-tool from git and configure it with PYTHON_VERSION=2.7 PYTHON=/usr/bin/python2.7 CXXFLAGS="-I/$HOME/.local/include -I/opt/local/include" CFLAGS="-I$HOME/.local/include -I/opt/local/include" LDFLAGS="-L$HOME/.local/lib -L/opt/local/lib" ./configure --prefix=$HOME/.local --with-boost=$HOME/.local/ --with-numpy=/Library/Python/2.7/site-packages/numpy-2.0.0.dev_3b3735d_20111219-py2.7-macosx-10.7-x86_64.egg/numpy/ --with-scipy=/Library/Python/2.7/site-packages/scipy-0.11.0.dev_c2ff01c_20111219-py2.7-macosx-10.7-x86_64.egg/scipy/ --disable-debug --disable-openmp Compile it a very long time and then install it. Of course, I use the latest Xcode 4.2.1. I found it really hard to get graph tool running on Lion. Cheers, Sebastian -- Sebastian Weber Group of Cell Communication and Control Freiburg Institute for Advanced Studies - FRIAS School of Life Sciences - LIFENET Albert-Ludwigs-Universität Freiburg Albertstr. 19 79104 Freiburg T.: +49-761-203-97237 Fax:+49-761-203-97334