By some small miracle, I managed to get the installation to work on my MacBook Pro for work. I'm still struggling with my MacBook Air. Wondering if anyone has any suggestions. Here's what I'm seeing. $ sudo port install py27-graph-tool---> Computing dependencies for py27-graph-tool ---> Fetching archive for py27-graph-tool ---> Attempting to fetch py27-graph-tool-2.2.18_2.darwin_11.x86_64.tbz2 from http://packages.macports.org/py27-graph-tool ---> Attempting to fetch py27-graph-tool-2.2.18_2.darwin_11.x86_64.tbz2 from http://mse.uk.packages.macports.org/sites/packages.macports.org/py27-graph-t... ---> Attempting to fetch py27-graph-tool-2.2.18_2.darwin_11.x86_64.tbz2 from http://lil.fr.packages.macports.org/py27-graph-tool ---> Fetching distfiles for py27-graph-tool ---> Attempting to fetch graph-tool-2.2.18.tar.bz2 from http://distfiles.macports.org/py-graph-tool ---> Verifying checksum(s) for py27-graph-tool ---> Extracting py27-graph-tool ---> Configuring py27-graph-tool Error: org.macports.configure for port py27-graph-tool returned: configure failure: command execution failed Please see the log file for port py27-graph-tool for details: /opt/local/var/macports/logs/_opt_local_var_macports_sources_rsync.macports.org_release_ports_python_py-graph-tool/py27-graph-tool/main.log To report a bug, follow the instructions in the guide: http://guide.macports.org/#project.tickets Error: Processing of port py27-graph-tool failed Digging into the log file, I see the place where things go off the rails. :info:configure Command failed: cd "/opt/local/var/macports/build/_opt_local_var_macports_sources_rsync.macports.org_release_ports_python_py-graph-tool/py27-graph-tool/work/graph-tool-2.2.18" && ./configure --prefix=/opt/local --with-boost=/opt/local :info:configure Exit code: 1 :error:configure org.macports.configure for port py27-graph-tool returned: configure failure: command execution failed :debug:configure Error code: NONE :debug:configure Backtrace: configure failure: command execution failed while executing "$procedure $targetname" :info:configure Warning: targets not executed for py27-graph-tool: org.macports.activate org.macports.configure org.macports.build org.macports.destroot org.macports.install :notice:configure Please see the log file for port py27-graph-tool for details: /opt/local/var/macports/logs/_opt_local_var_macports_sources_rsync.macports.org_release_ports_python_py-graph-tool/py27-graph-tool/main.log Running those commands myself, I see the following from the configure statement: ... ================ Detecting python ================ checking for a Python interpreter with version >= 2.6... python checking for python... /opt/local/bin/python checking for python version... 2.7 checking for python platform... darwin checking for python script directory... ${prefix}/lib/python2.7/site-packages checking for python extension module directory... ${exec_prefix}/lib/python2.7/site-packages checking for python2.7... (cached) /opt/local/bin/python checking for a version of Python >= '2.1.0'... yes checking for a version of Python == '2.7.1'... yes checking for the distutils Python package... yes checking for Python include path... -I/System/Library/Frameworks/Python.framework/Versions/2.7/include/python2.7 checking for Python library path... -L/System/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/config -lpython2.7 checking for Python site-packages path... /Library/Python/2.7/site-packages checking python extra libraries... -ldl -framework CoreFoundation checking python extra linking flags... -u _PyMac_Error /System/Library/Frameworks/Python.framework/Versions/2.7/Python checking consistency of all components of python development environment... yes =========================== Using python version: 2.7.1 =========================== checking for boostlib >= 1.38.0... yes checking whether the Boost::Python library is available... no configure: error: No usable boost::python found I tried uninstalling and reinstalling boost different ways and to no avail. Definitely out of ideas. Any pointers would be greatly appreciated! Chris